张春侠,燕宇航,堵爱农,赵旭飞,陈太杰

• 1:安庆师范大学化学化工学院

摘要(Abstract)：

文章以2-甲基苯并噻唑为母核，经硝化、催化氢化、Sonogashira偶联、Knoevenagel缩合等反应，以及烯炔双链接桥设计来合成了一种荧光探针N-BPA。光谱分析发现，该探针分子具有148 nm的较大Stokes位移，可以有效避免探针成像过程中的自猝灭现象，同时具有1.285×10~4L/mol的较高拟合结合常数，说明探针分子与苦味酸的结合程度随浓度增加明显增强，其检测限达到5.42×10~(-4) mol/L。此外，其他常见硝基化合物对探针分子无明显干扰，表明该苯并噻唑类荧光探针具有较好的苦味酸识别能力。

关键词(KeyWords)： 荧光探针;苯并噻唑;苦味酸;Stokes位移

Abstract:

Keywords:

基金项目(Foundation): 安徽省高等学校自然科学研究重点项目(KJ2016A425)

作者(Author): 张春侠,燕宇航,堵爱农,赵旭飞,陈太杰

DOI: 10.13757/j.cnki.cn34-1328/n.2025.03.012

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